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Imikhiqizo

IHordenine hydrochloride

Incazelo emfushane:

Imininingwane ebalulekile:
Igama: Hordenine hydrochloride

ICAS NO: 6027-23-2
Ifomula Yamamolekhula: C10H16ClNO
Isisindo Yamamolekhula: 201.69
Ifomula yokwakhiwa:

detail


Imininingwane yomkhiqizo

Amathegi womkhiqizo

Inkomba yekhwalithi:

Okuqukethwe: 98.5%

Ukubukeka: i-crystalline powder emhlophe

Umyalo:

Kutholakale enqwabeni yezitshalo, i-hordenine iyi-alkaloid exhumana nohlelo lwe-adrenergic ukukhuthaza ukugxila nokugxila phakathi kwabanye. Ngenkathi ucwaningo lwe-hordenine HCl lungagcini ngandlela thile, kunobufakazi bokuqala bokuthi lo muthi ungaba i-adrenaline reuptake inhibitor, eyenza ukuhlangana okuvamile nezinye izidakamizwa nezinto.

Yize isha sha, i-hordenine HCl ithengiswa njengesishisi esinamafutha ngokusebenzisa umzimba othuthukisiwe. Ngeshwa, ezimbalwa zezifundo ze-hordenine HCl zenziwa kubantu noma nge-oral administration versus injection. Awekho kulawa maqiniso asho ukuthi i-hordenine HCl ayisebenzi, kepha kuphela lezo zimangalo zokushiswa kwamafutha ze-hordenine okufanele zithathwe nenhlamvu kasawoti.

IHordenine hydrochlorideinemiphumela yokuphumuza imisipha ebushelelezi ye-bronchial, ukuthola imithambo yegazi, i-vasopressor, ukukhuphula umfutho wegazi nokuvuselela uhlelo lwezinzwa oluphakathi, futhi ingasetshenziselwa ukuqeda i-bronchitis ne-asthma ye-bronchial. Kungakhulisa ukungezwani nokunyakaza kwesibeletho, futhi kuyasebenza ngomthamo.

IHordenine iyinhlanganisela yemvelo yePhenethylamine eyenzeka ezitshalweni eziningi ezahlukahlukene, kepha ikakhulukazi utshani bebhali. Ifana ngokwakha ne-amino acid Tyramine. Iphikisana nokuqashwa kwe-beta-arrestin okukhombisa ukuthi kukhethwe ukusebenza. I-Hordenine ivimbele i-melanogenesis ngokucindezela ukukhiqizwa kwe-cAMP, okubandakanyeka ekubonisweni kwamaprotheni ahlobene ne-melanogenesis. IHordenine ingaba yisithiyo esisebenzayo se-hyperpigmentation. I-Hordenine iyisidakamizwa esisebenza ngokungaqondile esenza i-adrenergic. Ikhulula i-norepinephrine ezitolo. Ezingxenyeni ezingazodwa nakulezo zakhiwo ezinokuncishiswa kokuqukethwe kwe-epinephrine, umphumela we-hordenine umpofu kakhulu. Ukuhlolwa kwezilwane ezingaphelele (amagundane, izinja) kukhombisa ukuthi i-hordenine inethonya elihle le-inotropic enhliziyweni, inyusa umfutho wegazi we-systolic kanye ne-diastolic, ivolumu yokugeleza kwegazi, ivimbela ukuhamba kwamathumbu kepha ayinamphumela ekuziphatheni kwengqondo kwamagundane. IHordenine ibhekwa njengokuvikeleke kakhulu futhi ibekezelela kahle kubantu abadala abaphilile. IHordenine iyinhlanganisela ye-nootropic esebenza ngokulinganayo ekuthuthukiseni ukuqonda nokusebenza kwezemidlalo.

Njengohlobo lwe-benzylidene isoquinoline alkaloid, luhlobo lwe-benzylidene alkaloid kusuka ku-isoquinoline mama nucleus.Umthelela ohlelweni lokujikeleza kwegazi nomphumela we-urea ekuhlukanisweni kwenhliziyo kwe-guinea pig kungakhuphula ukugeleza kwegazi okuhamba kancane, kukhuphule izinga lokushaya kwenhliziyo kanye ne-myocardial ukusika kwe-contraction amplitude.Kwezinso nendlebe kanogwaja, ukugeleza kokunisela kungakhuphuka kancane, kuyilapho okwengxenye yangemuva kusobala kakhulu. 

Iphakheji: Isigubhu sekhadibhodi esingu-25kg

Isitoreji: gcina endaweni yokugcina impahla eyomile nenomoya

Amandla wonyaka: 100 amathani / ngonyaka


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